Focus on sarcomas
نویسندگان
چکیده
منابع مشابه
Advances in the Management of Soft Tissue Sarcomas - Focus on Emerging Therapies
Soft Tissue Sarcoma (STS) encompasses a number of different clinical entities and is a rare form of cancer. This review focuses on treatment of extremity and trunk STS (excluding gastrointestinal stromal tumors), focusing on more recent treatment updates. Early disease is managed by surgical resection as a definitive curative procedure, sometimes in combination with radiotherapy. Newer techniqu...
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HYBRID Ia MOLECULES ON RETICULUM CELL SARCOMAS
The reticulum cell sarcoma (RCS) 1 of S JL / J mice has been shown to express alien histocompatibility membrane antigens (1, 2). This form of tumor antigen is, by definition, present on cancerous, but not normal, syngeneic tissues. However, it differs from other forms of tumor-associated antigens because it is a normal membrane component of one or more strains allogeneic to the host (3). In the...
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Mclntosh (3, 4) has reported the successful filtrate transmission of 5 out of 8 strains of induced fowl tumors developed and transplanted in his laboratory, A number of other investigators (5, 6, 7, 10, 11, 12) have failed to transmit a single one of something over 27 induced chicken tumors, though many of these growths were easily transplanted and metastasized freely. Recently Duran-Reynals, S...
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Genetic aberrations in sarcomas 10 2.1. Cytogenetic alterations 10 2.2. Molecular genetic changes 13 2.2.1. Structural alterations of cellular proto-oncogenes 13 2.2.2. Gene amplifications 13 2.2.3. Alterations of tumor suppressor genes and loss of 17 DNA sequences 2.3. Hereditary predisposition 18 3. DNA amplification 19 3.1. Structure and mechanisms of DNA amplification 20 4. Methods for dete...
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ژورنال
عنوان ژورنال: Cancer Cell
سال: 2002
ISSN: 1535-6108
DOI: 10.1016/s1535-6108(02)00132-0